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Lyphar has acquired ISO, SGS, Kosher, Halal certificates and others honours.
10 years export experiences
Lyphar has been exported to countries all over the world since 2011.
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Lyphar got good reputation among customers, and pay much attention to after-sale service.
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retinoic acid
Xi'an Li Technology Co., Ltd. was established in 1 year. Its main products are sweet 201 biological additives and food raw materials, such as NMN, Soma, Nordil, RU-58841, Miku, etc. Our products are widely penetrated into food, beverage, food, food supplement, health care products and other industries.
Suddenly, we have 10 years of experience in this field and maintain good cooperative relations with old customers from all over the world and regions. Our company has independent import and export licenses, and has a good cooperative relationship with international express companies and some air and ocean freight agents, and has established timely and professional services for customers. The good performance of our customers can always provide better service and make our business easier.
Research on Retinoic Acid
The retinoic acid pathway plays an important role in many stages of heart development. The loss of key genes in the pathway can lead to abnormal ventricular trabecular formation, immature ventricular myocyte differentiation, and outflow tract defects. During mouse embryonic development, excessive retinoic acid will cause the atria to enlarge and the ventricles to become smaller.
These developmental biological clues provide important clues for the differentiation of pluripotent stem cells. How to clarify the time window of action of retinoic acid based on the cardiac development clues is one of the key factors regulating myocardial differentiation and maturity. The researchers analyzed the transcriptome of the three germ layers of mouse embryonic development on the 7.5th day, and found that most of the genes related to retinoic acid synthesis have been expressed at the primitive streak stage and continued to be expressed in the lateral mesoderm after the primitive streak migration. STRA6, a key gene for alcohol transport, only presents a specific expression pattern in the lateral mesoderm.
This indicates that the retinoic acid pathway has been prepared at the primitive streak stage in the early developmental stage, and it is triggered by STRA6 in the mesoderm of the lateral plate. The expression pattern of STRA6 represents the time window of retinoic acid.
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